Preheat your oven to 375°F (190°C).
In a skillet over medium heat, cook the ground beef until browned. Drain any excess fat.
Stir in the garlic powder, onion powder, oregano, salt, and pepper into the beef.
Grease a muffin tin with cooking spray or oil.
Spoon a tablespoon of marinara sauce into the bottom of each muffin cup.
Add a layer of the seasoned ground beef on top of the marinara sauce.
Sprinkle mozzarella and Parmesan cheese over the beef.
Bake in the preheated oven for about 15-20 minutes, or until the cheese is melted and bubbly with a golden crust.
Allow to cool for a few minutes before removing the bites from the muffin tin. Serve warm.
Variations & Tips
For a spicier version, add some chopped jalapeños or a pinch of red pepper flakes to the beef mixture. You can also experiment with different cheeses, such as cheddar or provolone, for a unique flavor profile. If you prefer a vegetarian option, substitute the ground beef with sautéed mushrooms or a meat substitute. These bites can also be made in advance and reheated, making them a convenient option for busy days or unexpected guests.